9

Fountain of Youth

 

     Anti‑aging, preserving our youth and reverse aging is a hot topic because it affects all of us. The people most interested in looking and feeling younger represent a growing segment of "Baby Boomers" past the age of 35. Visit a retirement home or convalescent hospital and you will see the ravages of aging in our senior citizens. By the year 2030 we will have 52 million Americans past the age of 70.

 

     Some people age more rapidly than others, because of a breakdown in our body's aging clock.  Our organs age, shrink in size and produce fewer hormones. This reduction in available hormones leads to a slow deterioration of all of our vital body systems. The declines in the Immune system, Reproductive, Neurological, Metabolic and Circulatory systems cause us to look and feel old.

 

     The “Fountain of Youth” involves understanding the aging process. There are eight critical hormones that decrease, as we grow older causing us to age rapidly. Reversing the clock is a matter of simply restoring these eight hormones to your youthful levels. I have seen numerous examples of people looking and feeling ten to twenty years younger within only ninety days.  Total replacement of all the deficient hormones is new, however hormone replacement therapy has been around for years.  All of the hormones replaced have been in our bodies and have been replenished by endocrinologists for decades.  Finally we are realizing the necessity to replace all of the hormones at the same time to a more optimal physiologic level.

 

     Dr. Eugene Shippen, author of “The Testosterone Syndrome” said hormones are “total body hormones”, not just sex hormones.  Men and women have estrogen and testosterone receptors in every cell of the body.  Men have three times more estrogen in the brain than women.  As men age testosterone declines.  The healthiest men and women have naturally high hormone levels.  Individuals with the lowest hormone levels have the poorest health.  Successful men who are type A, energetic and not needing much sleep have high testosterone levels.  There are women with naturally high estrogen levels with femine successful traits. 

 

Any deficient hormones require natural supplementation: The results I obtained with oral Growth factors led me on to the pursuit of analyzing each of the critical hormones.  I had my levels measured for DHEA, Human growth factors by IGF-1 and HGH, Total Testosterone & Free Testosterone, Melatonin, Pregnenolone, Thyroid, Progesterone and Estrogen.  Each of these levels should be checked by blood, urine and saliva very carefully because with aging, there are certain optimum levels that we need to maintain (see section at end of chapter).

 

Lets go into detail now about each of the critical hormones known to slow or reverse the aging process:

Pregnenolone

     Pregnenolone also known as Preg is considered the Grandmother hormone because it can be converted by the body into DHEA and Progesterone and over 150 other important natural steroid hormones.  Preg helps keep our brains functioning at peak capacity. It is a potent memory enhancer that improves concentration and fights mental fatigue, depression and reduces arthritis. According to Ray Sahelian M.D., many people reported that Pregnenolone provided as much alertness as coffee.  It made them more focused yet relaxed. Pregnenolone must be taken in the morning because it increases alertness, mental clarity and heightened awareness.  It is best not to take at night because it could cause insomnia.  It will enhance and possibly increase levels of DHEA and progesterone.  

 

     Pregnenolone is produced from cholesterol. DHEA, testosterone, and estrogen are also made from cholesterol. Low cholesterol levels will not interfere with the maintenance of proper normal levels. However, as we age the ability to convert cholesterol to proper hormonal levels is a problem. Take supplements providing 2-10 mg per day to replace what you need to restore your levels. For people past the age of 50 you may take up to 15 mg per day.  Be sure to stay on low dosages of Pregnenolone.  At dosages over 25 mg per day, some people complain of irritability, headaches or insomnia.  At low dosages you may expect enhanced mood, euphoria, alertness and energy.  Pregnenolone adult blood levels should range between 20-150 ng/100ml or for Preg Sulfate 2.7-8 meg/100 ml.  Pregnenolone concentrates in the brain and central neural tissues over 70 times more that in the blood.  DHEA is only 6 times higher in the brain than blood, with more found in the peripheral tissues.  I have found it beneficial to take pregnonolone with other brain strengthen supplements including 5-HTP (a form of tryptophan), phosphatidylserine, phosphatidylcholine, NADH, DMAE, vitamin B5 and Ginkgo Biloba.

Testosterone

     The next critical hormone that slows aging is testosterone. Free and total testosterone is found naturally circulating in the bloodstream of baby boys creating the male testes and penis. Small amounts of testosterone produced in women's ovaries and adrenals provide energy, libido and a feeling of well being. Young teenagers and adult men have large increases in free testosterone followed by a gradual decrease after age 25 with a steady fall decade by decade.  In certain rare instances men maintain high testosterone at the upper end of the normal scale into old age and they are the healthiest mentally and physically, most vital individuals.

 

     A 73-year-old Doctor said, "I take testosterone because I want to feel the same way I did when I was in my prime. I want to have the same sexuality that I did when I was young. I want to maintain my muscle strength.  I want to feel vital.  Testosterone makes it all possible."

 

     Research during W.W II on testosterone showed the powerful effect on the immune system. A physician transplanted testes from a dying soldier into the abdomen of a soldier suffering from gangrene caused by a gunshot wound. The soldier would have died, but the gangrene was cured following the transplant of the testes. In 1934 a scientist isolated the testosterone make up and received the Nobel Prize. Discoveries in 1951 reported that testosterone improves nitrogen balance, increases muscle mass and repairs damaged bones and ligaments.

 

     The first important study on men given testosterone for symptoms of aging was reported in 1944 by Drs. Heller and Myers in the JAMA 126(8) 472-7.  In twenty men treated for low testosterone levels, after only three weeks nearly all symptoms had been cured including insomnia, depression, crying spells, suicidal tendencies, inability to concentrate, palpitation, headache, fatigue, muscle pains, urinary problems, and loss of normal sexual function.  Yet this landmark study was forgotten or ignored until recently!

 

     In the 1960's it was discovered that testosterone lowers cholesterol, improves abnormal EKG's of cardiac patients, helps claudication (clogged leg arteries) and angina pectoris (chest pain) ‑clogged heart arteries. Free testosterone maintained at youthful levels protects men against atherosclerosis ‑hardening of the arteries. Testosterone also improves diabetic retinopathy, helping eyesight, lowers insulin requirements and enhances glucose tolerance of diabetic patients.

    

     Testosterone decreases body fat, improves waist‑to‑hip ratio of fat and enhances lean body mass. It has a protective effect against autoimmune diseases such as lupus and rheumatoid arthritis. Studies show that men with high testosterone levels live longer, healthier lives and maintain sexual potency. Men over 50 years old with low testosterone levels, in a double blind, placebo‑controlled study, were given either replacement testosterone for 90 days or a placebo. They found the hormone renewed strength, improved balance and increased libido. Restoring testosterone increased red blood cell count, lowered LDL ("bad") cholesterol and enhanced feelings of well being.

 

     In July 1996 New England Journal of Medicine researchers discovered that testosterone significantly enhanced muscle size and reduced body fat even in men who do not exercise or go on a diet. Three groups of male weight lifters did the same exercise or no exercise. The men were given testosterone or placebo every week for ten weeks. The men given testosterone had much more muscle whether or not they exercised.

 

     The American Journal of Physiology reported in men age 67 after only 4 weeks with the addition of testosterone had an increase in leg muscle strength and restored muscle size. In another study at the University of Washington, men past the age of 60 who were given testosterone for three months lost fat and gained muscle without going on a diet!

 

Sexual pleasure, performance assessment

     Is your sex life or desire for sex declining as compared to your libido at age 20?  Women, do you have less satisfaction with sex?  Do you have reduced or dry vaginal lubrication associated with uncomfortable intercourse?

     Men, are you finding a decrease in spontaneous early morning erections? Are you experiencing a decrease in fullness of erections and volume of ejaculate?  Do you have difficulty in starting an erection or in maintaining a full erection?

 

Loss of sexual function:  We have been hearing a lot in the press about a prescription drug used for sexual performance and we recognize what a critical problem this is in millions of men who have developed sexual impotency.  Impotency is a very common problem in our country mainly because of clogged arteries and high cholesterol that narrow the arteries to the male organ.  Diabetes, nerve damage or blood pressure medications can cause impotency.  The medications reduce blood flow so much that a man can’t achieve an erection.

 

     The prescription drug, Viagra, is a method to regain short-term sexual potency by providing extra blood flow to the penis. It could cause side effects such as headaches, changes in vision and even risk of death in some frail people.  The drug is a temporary solution to an alarm sign that aging is setting in prematurely.  Correct the weakness caused by aging and you can restore potency and vitality.

 

A recent survey of over 4,000 males showed a 50% difference in the frequency of orgasms between different age groups:        

 

Orgasms per month

20 to 39 years old -  9 to 10 orgasms per mo.

40 to 49 years old -  7 orgasms per mo.

50 to 59 years old -  5 orgasms per mo.

59 to 79 years old -  3 orgasms per mo.

 

     An orgasm more than twice a day, seems to draw on the body's nerve energy, and dramatically reduces our recuperative powers.  Fortunately, 60 orgasms a month is above the study groups average.  And it's unlikely that you'll have to worry about curbing your sexual appetite, if we recommend that you have less than three orgasms a day!  Try having five to six orgasms a day and you will notice a reduction in your recuperative powers.  As proof, your sleep requirements go up with frequent orgasms. 

 

     Your ability to overcome simple illnesses like colds and flu is affected by excessive orgasms as well.  You will notice it takes longer to be free of symptoms.  Your immune system, life systems and muscle building depends on the same adaptive energies that are released after having an orgasm.  So leave yourself some energies.

 

     Thirty-four percent of the men on a high fat, high cholesterol diet, past the age of 65 become sexually impotent.  They are unable to achieve an erection, and enjoy orgasm because the blood vessels in the penis are clogged with cholesterol.  The cholesterol plaques restrict adequate blood flow to the male organ.  This blood flow is essential for normal sexual relations into advanced ages. 

 

     In parts of Japan, when the farmers retire at the age of 65 or 70 years of age, it's very common for the men to take a bride of age 30 and begin a family.  Their diet of rice, grains, vegetables, and fruit (with very little meat, and virtually no eggs or dairy products) allows the men to maintain healthy circulation free of any cholesterol plagues in their arteries.  They also live long enough (age 90 to 100) to raise their children and see them graduate from college.  In the contrast, to the typical American male senior citizen, he gets married at age 30, is unable to enjoy sex by age 55 and dies prematurely at age 70.  The death rate from heart attacks and strokes, is greater than 50% of our population due to high cholesterol, high fat diets.

 

Sexual Dysfunction and Solutions

     Getting to the cause of the problem can solve these physical disorders leading to impotency.  Avoidance of foods high in cholesterol like meat, chicken, fish, eggs, and cheese replaced with fresh vegetables, fruit, rice, beans and sprouts in the diet along with HGH replacement and testosterone will unclog arteries to the male organ and restore circulation throughout the body. It would be best to overcome the most common causes of sexual dysfunction by correcting the diet and hormones. Improved blood sugar control will reduce the incidence of diabetes.  Over 65% of those on blood pressure medications can be off medicines and back to normal within 30 days using the Grow Young & Slim plan. As blood flow is restored men can regain sexual potency.

 

Hormones improve sexual function in men & women  

     Depressed hormone levels is yet another cause of impotency.  When the men past the age of 40, in Dr. Chin & Terry’s study, restored their hormone levels, they could function sexually as if they were twenty years younger. HGH, Testosterone, Progesterone and DHEA are the ultimate aphrodisiacs.  Testosterone along with DHEA is responsible for the sex drive of both men and women, stimulating our desire for sexual activity and orgasm.  It is testosterone, not estrogen that causes the heightened erotic sensitivity of the clitoris, breasts, and nipples. Testosterone encourages a woman to go after a man. She becomes more sexual, more responsive and more assertive. It does not influence the frequency of intercourse. Testosterone improves self‑confidence and serves as an antidepressant in women.  Testosterone is regulated by LHRH- (Luteinizing Hormone Releasing Hormone), the director of testosterone to give you desires.

 

      PEA- (phenylethylamine) is the hormone that releases when you see someone you're interested in, causing attraction to the opposite sex.  

 

     DHEA contributes to the sex drive in both men and women, increasing your libido by sensitizing your erogenous zones to touch and promoting positive sexual scents called pheromones.  Dopamine increases our receptivity to pleasure.  High serotonin levels reduce our interest in sex and inhibit orgasm in both sexes.  Low serotonin levels caused by diet pills can increase aggression and excessive sexual aberrations.

 

     Estrogen is a warm, receptive, willing, passive and seductive hormone. Progesterone and prolactin are nurturer hormones, reducing sex drive. Oxytocin increases during touch creating bonding and a feeling of love. Vasopressin is a peptide like hormone that bonds and enhances parenting feelings, according to Dr. Theresa Crenshaw.

 

     The American Journal of Physiology reported crossover studies where the placebo group was given testosterone and the group given testosterone was taken off. 67-year-old men reported being more aggressive and energetic at work. The men with normalized testosterone levels found that their relationships improved with their wives because of better sexual performance, initiation of sexual intercourse and increased ability to maintain an erection.

 

     In older men, ages 31 to 80, high levels of Sex Hormone Binding Globulin reduced free testosterone in 74% of the men complaining of sexual dysfunction.  Nearly 80% of the men had a reduction in libido (interest in sex), difficulty in getting or maintaining an erection, rarely had early morning erections and 92% experienced a reduction in sexual satisfaction.

 

     In addition, these men with low free testosterone levels reported fatigue, depression, irritability, aches, pains and stiffness. A significant drop in free testosterone can occur as early as age 40.  At age 60, 18% of men are impotent and at age 80, 75% are impotent. Once a man becomes impotent he loses his drive for life, has impaired erections, his muscles become thinner, he becomes depressed and mental acuity fade.

 

     All healthy males get erections, mostly during the REM dream stage of sleep every night without exception.  These erections are not stimulated or associated with the content of dreams.  The penis of a medically fit man erects more than 10 times a night!  Erections occur in cycles lasting about 30 minutes, although the penis is not fully erect the entire time.

 

     If a man wakes up in the middle of the night with an erection this is a normal healthy sign.  If he gets an erection early in the morning, he can rest assured that his penis is in good working order. If he is not having good erections during sex, any difficulty is probably psychological. That is assuming random erections occur. You can do a simple test using postage stamps to test for erections. Take a roll of postage stamps and wrap it around the flaccid penis before sleep. If the perforations between the stamps tear by morning, then the man had an erection during the night. If no erection, then the problem is organic and physical.

 

The following 3 tests can determine what type organic problem exists:

 

1.       Vascular disorders are the most common causes of penile erection dysfunction. High cholesterol levels will clog arteries that bring blood to the penis or by leaks in the venous system that result when the blood in the shaft of the penis drains out prematurely. A doctor can use one simple injection of vasoactive drugs (Papaverine or Prostaglandin‑E) to determine whether the arterial system is intact. The drug produces an immediate erection in healthy men regardless of the mental factor. The penis either gets hard or it does not. If it does not, then you need to clean the arteries. Change to a cholesterol free vegetarian diet, take soluble fibers, reduce alcohol, stop smoking, especially before sex, increase free testosterone to reduce atherosclerosis and see a doctor for treatment.

 

2.       The test for neurological problems is performed by inserting a gloved finger one-inch into the man's anus to feel the sphincter muscle and with the other hand gently squeezing the tip of the penis. If the nerves to the penis are working properly, squeezing the tip of the penis will cause the anal sphincter to contract firmly against the finger.

 

3.       Hormonal disorders are the third common cause of erection failure. Diabetes, overactive or under‑active thyroid and low HGH levels can cause erection failure.  Lack of testosterone can also cause erection failure. Saliva or blood can test these hormone disorders. Restoring hormone levels to normal levels can solve these erection problems.

 

     L-Arginine the amino acid at 3 to 6 grams a day can restore part of the nitric oxide cycle necessary for achieving erection, according to Julian Whitaker MD.  Be sure to take L-Lysine with L-Arginine if you tend to develop fever blisters or herpes because this balance is necessary to have proper immune system function.

     The herbs Avena Sativa (Green Oats), Nettles, and Saw Palmetto can restore free testosterone to the youthful range for men and women. To enhance testosterone Tribulus terrestris fruit extract at 1,000 to 2,000 mg dosage helps LH factor to increase testosterone.  Avena Sativa, which is sprouted green oats, and the herb nettles removes sex hormone binding globulin and releases free testosterone. One gram per day of the B‑Vitamin niacin also reportedly helps lower Sex Hormone Binding Globulin and releases the free testosterone.  The herb- Epimedium Sagittatum, sometimes referred to as “Horny Goat” is an ancient Chinese remedy for restoring sexual performance, sexual appetite for enhanced male and female sexuality, according to Sexologist, Patti Britton.  Some have referred to this herb as the herbal Viagra, because it enhances erection in men and stimulates sexual function in women.  When Epimedium Sagittatum is used in combination with Avena Sativa and Tribulus terrestris fruit it has been shown to help men and women enhance their love lives and relationships. Give these herbs about two to four weeks to build up and restore your testosterone and you will feel the difference!

 

     Avena Sativa is an extract of sprouted green oats (oatmeal seeds sprouted).  It is available in capsule form and in sublingual liquid form.  The saying “sow your oats” was first mentioned in biblical times and its powerful sexual enhancing and anti aging powers.  Avena Sativa was first rediscovered in China when it was found that if carp, a colorful pond fish were fed green oats, they became lively, mated, and multiplied.  The researchers tried the green oats and they noticed they became lively and frisky!  Studies in Hungary showed men given Avena Sativa increased the excretion of testosterone in the urine indicating an increase in free testosterone.  Older men given Avena Sativa notice an increase in libido (interest in sex), increase in the need to have intercourse with their mate, and frequent night and morning erections.  About one third of the men had firmer, stronger erections and less incidence of impotence.  Women who were already fairly comfortable with sex, noticed increased intensity of orgasms, and a desire to have sex with their mate.  Women who were not in a relationship and were uncomfortable with sex reported becoming irritable when using Avena Sativa.  This is no surprise in women who had no outlet for there increased sexual energies, to become irritable.  It this situation use the green oats to divert your energy into exercise or work. 

 

     Surprisingly it takes very small amounts of testosterone to physically maintain an erection and enjoy sex. The problem is that a man low in testosterone may simply not care enough to pursue it. Once testosterone levels are replenished a man will find that he has recaptured a healthy interest in sex. Men have gone from zero libidos to a vigorous sex life within ten days.

 

     The saying, "if you don't use it you lose it" applies with testosterone. Frequency of sex increases testosterone in both male and females after sex.  Salivary testosterone concentrations were measured in a study of four couples on a total of eleven evenings before and after sexual intercourse and eleven evenings when there was no intercourse. Testosterone increased in men and women when there was intercourse and decreased when there was none. Your relationship plays a meaningful role in immunity, health and longevity.  This may account way married men, with active sex lives, had higher testosterone levels and live longer than single men.

 

     In most people, the natural herbs and vitamins restore youthful testosterone levels.  My free testosterone increased dramatically within four weeks using herbs including Avena Sativa, Saw Palmetto, nettles and ionic minerals with zinc.  When I tested my Free Testosterone level at age 41, it went from severely deficient with a level under 1.3 ng/dl to over 22 to 28 ng/dl which is ideal for a young 20 year old man, based on blood tests. Prior to taken Avena Sativa, nettles, saw Palmetto, and zinc I had almost a complete loss of interest in sex, even though I could achieve erection and perform intercourse.  After only 4 weeks I experienced a healthy increase in libido, strength and muscle density while taking the herbs!  I continue to take my herbs, natural hormones and minerals improving every year as I am aging healthy.

 

     If you have low testosterone levels, have your doctor check your FSH and LH.  If both are low you might need to be given a hormone called HCG chorionic gonadotrophin which stimulates an increase in FSH and LH to cause the testicles to manufacture testosterone which can solve the problem within a month. Your testicles might even enlarge to overcome the condition of Hypogonadism.

 

     In older men and women past 40 with low free and total testosterone levels, along with the herbs use replacement therapy with a prescription from your doctor.  Injections of testosterone are the worst form of replacement because it can go too high and then drop too low.  It is best to take testosterone as a cream, gel or patch.  The compound pharmacist can provide natural testosterone of 10 mg and up to 100 mg per gram for men and 1 or 2% per gram or 3 to 6 milligrams per gram of testosterone for women in a gel or transdermal cream form.  The first month prescription might be at the higher dosage to overcome any severe deficiency state and then the second or third month after strength, muscular mass gain, sex drive, energy and mental focus return it would best to reduce the dosage to the lower end.  Over time it is best to monitor the men or women with monthly saliva and blood tests for testosterone (free unbound and total) to be sure you are in the ideal range.  Too much testosterone from injections can be a problem for men as well as women because the excess can aromatize or convert over into estrogen and too much DHT (dehydrotestosterone).  The excess estrogen can cause a loss of sex drive, performance and fatty weight gain.  Too much in women could cause masculinization effects. This is why testosterone is a prescription controlled substance because it should be monitored closely if it is needed.  Rub the cream after showering into the scrotum of men (the skin of the scrotum is thin allowing 10 times the absorption rate) or inside the inner thighs, small amounts added to the external genitalia area (2 or 3 times a week) or the tummy area for women.  The neck and the bend of the inside arm opposite the elbow gives increases in absoption.  This can improve the quality of life within a few weeks when applied to various parts of the body five times a week for adults.

 

     Many women say that by taking herbs like avena sativa, epimedium sagittatum and testosterone cream they feel more womanly than ever before.  Over 86% of women past the age of 45 report a decline in libido and sexual activity according the American Journal of Medicine 1995; 98(1A).  Many women report a decline is sexual interest as early as the late thirties, corresponding to their drop in testosterone levels.  Women are packed with testosterone receptors in the nipples, vagina and clitoris.  If she has adequate levels of testosterone her sexual feeling will be intensified toward her mate.  If low, she may feel complete sexual deadness.

 

     Women over the age of 60 given 1 mg testosterone in cream applied to the skin daily for 30 days reached the increased their free testosterone to upper levels for young 23 year old ovulating women. They experienced a dramatic improvement in libido- intensity of sexual drive, intensity of orgasm, sexual arousal, satisfaction, pleasure, frequency of fantasies during a two-year study in postmenopausal women when compared to placebo.  Women given a 50 mg testosterone pellet implanted in the abdomen restored libido in 10 to 14 days and lasting for 3 to 6 months without virilizing side effects.  This study sited reasons for decline in testosterone including aging of the adrenal gland and reduced ovarian secretion of testosterone production after age 30, the use of the oral contraceptive pill or estrogen replacement suppressing LH-hormone that increases binding globulin interfering with free testosterone.  And ovaries surgically removed, chemotherapy, or radiation. The best response was in women over the age of 30 with deficient levels - Journal of Clinical Endocrinology & Metabolism June 1999: 84: p. 1886. 

 

     Dr. Eugene Shippen helped a lady named Janice who had survived uterine cancer following hysterectomy, radiation, bladder leakage, and thinning vaginal lining causing painful intercourse.  In just a few weeks following the use of pure testosterone cream combined with a natural form of estrogen applied to the vagina, vulvar area she had greater energy throughout the day.  She felt stronger, and she began to feel sexual desire again.  It became possible to have intercourse with her husband without pain, because her vagina became pink, moist, strong and plumb as when she was young.    

 

     Supplemental herbs with Saw Palmetto using 160 mg morning and night will benefit those with enlarged prostate and male pattern baldness because it inhibits the effects of 5-alpha reductase to protect the prostate and reduce the loss of hair.  Saw Palmetto helps keep DHT (dihydrotestosterone) in a free state, non-binding, not to high or to low.  Saw Palmetto prevents the conversion of testosterone to dihydrotestosterone.  This helps to avoid the any negative affects of acne, balding, virilizing effects or prostate enlargement.  However the use of Saw Palmetto may slow muscle gains if you’re weight training, and worsen sexual performance because it reduces the production of testosterone.  However, use Saw palmetto for enlarged prostate that is pressing on the nerves and blood vessels that feed the penis reducing erectile function. Relieving the condition may help men attain an erection.

 

     Eugene Shippen MD is convinced that men with prostate problems actually need testosterone replacement with saw Palmetto.  He has seen a number of men who have improved and reduced symptoms associated with enlarged prostate once their testosterone levels normalize upwards.  He gave the example of a sixty-six year old man named Sam following bypass surgery for clogged arteries. He had a decline in sex function, waning energy, and persistent urinary problems (getting up in the middle of the night to urinate constantly) and came to him for help.  Dr. Shippen put Sam on Saw Palmetto, which helped decrease the frequency and increased the flow.  However, the biggest improvement occurred after Sam started taking testosterone daily prescribed by Dr. Shippen and after only a few weeks, Sam was urinating less often with better muscle control.  Sam’s sex life got much better, sometimes making love twice in one day.  He felt stronger, more stamina, golf game improved, and has more get up and go.  

 

     Unfortunately, most men have a drop in Free testosterone, as it becomes bound and unusable as we age, by Sex Hormone Binding Globulin (SBBG).  To make matters worse, testosterone begins to aromatise or convert over into estrogen, causing a further decline.  The good news is we can correct these hormone imbalances.

 

     The combination of bound and free testosterone is total testosterone. Doctors mistakenly usually only check total testosterone.  However, it is the free testosterone that is the only biologically active part from a health muscle density versus fat ratio and sexual point of view. The free testosterone is very active when it is weakly bound to albumin protein.  Free testosterone bound to Globulin protein is tightly bound and rendered inactive.  Even if an adult has total testosterone levels above normal, but has below‑normal free testosterone, your sex drive will probably be sluggish and nonexistent and your body fat will increase.

 

     Think of free testosterone as the only active part with high impact on your health.  Testosterone significantly increases following resistance exercise workouts.  The resting testosterone (hours after exercise) was found to decrease when excess protein was added in the diet.  As protein increased, resting testosterone levels decreased. Low fat intake under 10%, decreased testosterone.  It is important to use weight training and the recommended herbs and supplements instead of trying to increase testosterone by adding fat; otherwise you may increase estrogen levels. The following herbs, water rich diet with weight training will maintain proper levels of testosterone and to suppress estrogen as you age.

 

Anti-Estrogen steps to reduce the bad kind of estrogen

     Many men and women have a major imbalance cause be an excess amount of estrogen present in their blood stream and fatty tissues.  Too much estrogen in your blood and tissues cause you to gain fat, loss muscle, and reduce sexual performance or enjoyment.  Women have too much of the wrong kind of estrogen because of artificial synthetic hormone replacement and a high fat diet. Men have three times more estrogen in the brain than women. However, most older men suffer decreasing testosterone and have far too much estrogen by ratio, decreasing or nullifying the benefits of testosterone!  Alcohol makes matters worse by inhibiting your body’s ability to clear estrogen from the blood stream and also decreasing zinc.  Grapefruit may also inhibit your liver’s ability to breakdown estrogen.  However, broccoli and cauliflower stimulate the burning off of extra estrogen.  Soy products allow the liver to excrete more excess estrogen.  Isoflavones found in soy products like genistein, and diadzein block the receptor sites where estrogen binds to cells, which helps prevent estrogen from accumulating in your body.  Red grape skin extract, Resveratrol improves the liver P450 system to effectively remove excess estrogen.  Vegetables like bell peppers and fruit rich in vitamin C complex reduce the aromatase enzyme responsible for converting too much estrogen from testosterone. 

 

     A product called Di-Indolin providing diindolylmethane, that is believed to be the most active cruciferous substance (broccoli, cauliflower, kale) for promoting beneficial estrogen metabolism, helps increase the ratio by 75% of the “good” 2 hydroxy estrogen’s which have an affinity to bind blood proteins (SHBG), leaving greater levels of free testosterone.  Diindolylmethane also dramatically decreases the “bad” estrogen 16-hydroxyestrone by 50%.  This product is best for athletes and bodybuilders or men taking testosterone replacement whom are interested in getting the best possible results to manage estrogen, to have a lean hard strong body. 

 

     Chrysin taken 4 times a day (a supplement from the passion flower derived from vegetables rich in bioflavonoid) and Querctin taken morning and night absorb the enzyme that produces more estrogen. 

 

     The mineral zinc inhibits the aromatase enzyme that converts testosterone into excess estrogen.  Many men can restore normal balance of testosterone to estrogen with zinc gluconate at 50 mg twice daily until you feel improvements in libido and nighttime erections, then reduce to using 50 mg of zinc once a day. Nearly 15 mg of zinc is lost with each ejaculation during sex.  We must take a highly absorbable form of zinc to replace this loss (depending on how sexually active). Zinc also increases total testosterone production.  To balance zinc add Manganese Gluconate of 50 mg a day and eat more tropical fruits rich in manganese like mangos and pineapples. 

 

    Fat cells are loaded with aromatase storing large quantities of estrogen.  The higher your percentage body fat, the more estrogen you can produce and the fatter you will be unless you control your diet and use supplements to lower estrogen production.  You will reduce body fat with our water rich diet of ten or more servings of vegetables, salads, soups, and fruit a day. Add the suggested supplements from the weight loss section of this book like chitosan, pyruvate and slim trim herbs to increase metabolism and reduce appetite.  As you reduce the pounds of fat your estrogen conversion will be reduced and symptoms of male menopause and female disorders associated with estrogen dominance will vanish!  It will actually become easier for you to lose weight with proper hormone balance, correct eating, supplementation and exercise.  You must reduce the use of “dry” carbohydrates, grains, wheat and processed carbohydrates because they tend to bind testosterone.  Whereas the good water rich carbohydrates of vegetables and fruit create the proper balance of estrogen and testosterone. 

 

     Fish is high in L-Dopa and helps release dopamine and enhance testosterone levels.  However, eat only small amounts of fish so you don’t clog up your arteries in the male organ with cholesterol leading to impotency (read our section on cholesterol in fish and chicken).

 

     Androstenedione supplements gained national attention when it was reported that “home run king” Mark McGwire hit a record 70 home runs in a single season for 1998 with 68 home runs in 1999, while taking this amazing supplement to increase testosterone.  Androstenedione can boost strength, muscular size, and endurance. Oral use of 50 to 100 mg.-raised testosterone levels over 200%.  This was over twice as effective as DHEA in raising testosterone.  Androstenedione should only be taking before athletic events, or before sex and not more than three times a week.  If overused, the excess production of testosterone can convert into too much estrogen and reverse your benefits.  If you use androstenedione daily be sure to use follow the anti-estrogen steps listed above to prevent estrogen buildup.  Androstenediol is the more potent form of prohormone when compared to Androsenedione.  Combined they are effective if used two or three times a week.

 

     Have your level checked by both a simple saliva test (see below) and a blood test since you may pick up a deficiency or excesses on one method of testing better than the other.

 

     For blood tests we use quality national labs that specialize in hormone testing.  You will need a doctor’s orders for the blood test (check our web site www.aginghealthy.net for listing of doctors). If you use your own doctor have him or her check our web site to order the right tests.  If you don’t have a doctor familiar with comprehensive hormone testing contact one of our doctors listed on our web site to request the complete tests. The lab will send you a kit with tubes and instructions to go to your local hospital or blood draw station.  Send the sample to the lab and the payment for the tests to the doctor ordering the tests.  The male panel and female panel current fee is listed on our web site. The doctor also charges a fee to order the test and review the results of between $75 and $150. This fee is to be paid at time of test.  Our male panel was designed to be very complete (see lab section at end of this chapter).

 

 Saliva tests for free testosterone, DHEA, melatonin, estrogen, progesterone and cortisol can be provided by going to our web site www.aginghealthy.net or www.growyoungandslim.com where we list doctors and lab services. Tell them Health Wellness studios referred you.  They will charge your credit card (or you can send in a check) a fee of about $145 to $345 to have your key hormone levels checked by saliva. They will send you a test kit with collecting tubes for saliva that you send back to the lab listed in the instructions.  Our web site www.aginghealthy.net can also refer you to those doctors who can order the test and review them. Saliva tests are easy to collect and mail to the laboratory without involving clinic staff, no biohazard, no mess, and no blood, very convenient and economical.  If your having trouble getting the tests done contact us by sending a stamped return envelope for information to Health Wellness Studios 25422 Trabuco Road, Suite 105 # 141 Lake Forest, CA 92630.

 

     Saliva tests are accurate with over a 90% correlation to blood tests results. Saliva tests can measure the effects of supplements on certain hormones better than blood, because spinning blood separates out cells that may have 75% of the hormones.  Your supplements for testosterone or DHEA may be working, and blood tests are not the only way to pick up the improvements.  Saliva tests pick up the full tissue levels for hormones. We can measure other important hormones in saliva or urine including melatonin, estradiol, progesterone and cortisol.

 

     Testosterone, estrogen, progesterone and melatonin are cyclic, going up and down throughout the day, night and month. Saliva tests for free testosterone can be performed with three samples taken morning, afternoon and late night. A man's testosterone level is highest in the morning.  The levels change every 15 minutes. Testosterone can vary by 100 ng (serum) or more with variations from day to day by as much as 50%. By taking a series of samples we can accurately track the average range and a doctor can determine if you need replacement therapy. 

 

      Be sure you check with your doctor and your labs regarding ideal levels because different labs use different reference ranges.  Just compare your goal to the youthful levels for people age 20 to 30.  

 

     DHEA sulfate is very stable with very little change in levels from day to day. A single saliva test for DHEA can tell us if your levels are below ideal. We need to take supplements of DHEA along with other natural hormones and herbs to prevent the decline associated with aging. The addition of DHEA can convert into the necessary testosterone for women, as the body needs, yet men do not get much conversion of DHEA to testosterone. In fact, men tend to get too much estrogen from DHEA if they use too much (over 50 mg of DHEA per day). The herbs like Avena Sativa may completely restore the free and total testosterone to normal levels in most of the cases.  However, if it doesn't normalize your testosterone levels then see your doctor for a prescription of natural, micronized testosterone gel to solve the problem.  Contact us if you can’t find a doctor to help you.

 

     Women during menopause who have tried hormone replacement with estrogen and progesterone are starting to be given a small amount of testosterone which replenishes energy, libido and feeling good again. Also, women need testosterone to be healthy and maintain strong bones and proper balance.

 

Progesterone 

   By the age of 35, most women have 50% less of this critical hormone progesterone.  It continues to decrease with age until you are totally deficient. The supplement of natural progesterone in the cream (Endau from wild yam), has been manufactured to be identical to the female molecule.  It is a better choice real progesterone in place of synthetic progesterone like Progestins or Provera. Many women feel remarkably better using the natural cream or transdermal form of natural progesterone. Natural progesterone and testosterone increases bone density preventing osteoporosis.  Estrogen can only slow bone loss.

 

REDUCE MENOPAUSE and PMS SYMPTOMS

     Women are using powerful synthetic hormone replacement therapy pills prescribed by doctors and P.M.S. clinics with little regard to the potential long-term serious side effects.   These synthetic hormone pills increase the risk of cancer and blood clotting and under prescription.  Fortunately, there is an alternative, safe course to follow using diet and exercise.  Natural Progesterone with testosterone gel prevents osteoporosis, not estrogen.  Evidence showing the slowing of bone loss has been documented.  Pharmaceutical UPS grade natural Progesterone cream is non-prescription because it’s safe and proven to prevent bone loss and strengthen the bone.

 

     High protein diet, lack of sufficient exercise, and deficient hormones cause osteoporosis.  If you start a daily walking program today, with weight training two times a week, you can immediately replace lost bone material.  The high water, fiber rich diet centers meals on vegetables, soups, salads, rice and fruit, instead of around proteins like meat, fish, chicken, milk and cheese.  As you follow this lower protein diet your bones will begin to reabsorb lost bone material.  You will receive adequate protein from the nutrient rich live foods.

 

     Before and after x-rays of people with osteoporosis has demonstrated a strengthening of bones by reducing dietary protein and exercising daily.  Urine tests measuring calcium retention have shown immediate improvements of positive calcium balance (more calcium has been absorbed than lost).  People on a high protein diet who do not exercise lose more calcium out of the urine than they take in from their diet.  Hormone pills by themselves are not the answer - diet and exercise are the key to building bones with age.

 

     Progesterone cream rubbed on your skin is absorbed 40 to 70 times more efficiently as compared to a pill. You need only a small quantity of cream rubbed into your fatty areas providing 10 mg to 20 mg. To equal this amount, you would have to take 200 to 400 mg as an oral pill, because the pill goes to the liver and is broken down into artificial metabolites. If you take a pill for progesterone (progesterone is fat-soluble) most of it is wasted, because the serum in the blood is water-soluble. You only get from the pill 5% of the 200 mg or 10 mg.  The progesterone in the cream is absorbed from the skin, directly into the red blood cells and then it reaches the tissues of the body.  Red Blood cells have a fatty membrane that allows transport of the progesterone where the body needs it.

 

     A saliva test is the best way to measure progesterone levels.  Saliva is fat-soluble and can transport in the fatty membranes of saliva tissue.  Blood serum is water-soluble and it will not show the increased levels from cream. Some doctors were led to believe the creams were less effective than pills based on blood tests. French doctors in 1997 measured breast tissue for progesterone levels and found it increased over 100 times using cream for progesterone. This proved excellent absorption using cream, even though blood levels showed no increase. This is because the transport of progesterone occurred by way of the red cells, not the watery blood serum plasma (clear golden fluid).  Only 1 to 9 percent of the progesterone bound in proteins is usable coming from pills via the ovaries.  Doctors had made the wrong conclusion about cream delivery.  They don’t even know to check the progesterone level with saliva.  Saliva carries the biologically active form of progesterone, DHEA, testosterone, melatonin and estrogen. 

 

Estrogen

     For years we have been aware that women have the need for replacement of estrogen and progesterone. Unfortunately, hormone replacement got a bad reputation because of side effects caused by using synthetic hormones like Provera, and Premarin to replace estrogen. Synthetic estrogen known as Premarin can cause irritability, fluid retention, and breast tenderness.  Pharmaceutical companies developed and patented a replacement using molecules that were not identical to the female estrogen molecules.  They could not patent natural triple or bi estrogen, so they produced and marketed synthetic altered molecules called “conjugated estrogens” derived from horse urine!  Nearly half of all women using synthetic estrogen stopped because of the concern of side effects reported.

 

     Fat in the diet will cause hormonal imbalances because an overproduction of estrogen.  These drastic hormonal imbalances can be corrected by following our low-fat diet, losing weight and by daily, long distance walking exercises. Synthetic estrogen hormones tend to cause weight gain by increasing fat production and increasing fluid retention.  This estrogen dominance without enough progesterone to create balance leaves excess estrogen binding to the receptor sites in the breast and uterine tissues, causing heavy or irregular periods, sore, tender breasts, water retention and even bouts with depression.  Also birth control pills worsen the situation by creating even more estrogen buildup which can stimulate and increase the risk of ovarian and breast cancer.

 

     The Grow Young and Slim Diet will help by reducing the harmful type of estrogen buildup, reduce fluid retention and reducing body fat from the hips, thighs and stomach.  You will look and feel great each additional month that you switch to soy-based phytoestrogens, progesterone and natural estrogen replacements.  Hot flashes can be reduced by exercise, which stimulates the ability to perspire and cools the body.  The low-fat diet along with increased water intake also may reduce symptoms and discomfort as your circulation improves.  Consistent, vigorous exercise increases the circulation of both estrogen and adrenaline, toning the skin and muscles

 

     You gain all the benefits using natural Triple estrogen or Bi estrogen such as Estriol at 80 to 90% ratio to Estradiol  and with or without Estrone at 3 to 10%, according to Dr. Jonathan Wright MD.  You can expect reduced hot flashes, night sweats, better memory, alertness, and reduced aging of the skin. Doctors are now starting to realize that it is really much better to prescribe natural Bi estrogen, to mimic the body’s needs. European studies prove the safety and benefits without side effects.  Thierry Hertoughe MD, from Belgium, represents four generations of physicians monitoring patients on natural hormone replacement to clinically youthful levels with excellent long term results and no side effects.

 

    Also, by using natural plant based estrogen with progesterone supplements, and vaginal cream you can avoid the usual side effects of synthetic hormones.  Dr. John Lee says “Never take estrogen of any kind unopposed to progesterone.” Always include the use of natural progesterone, soy-based plant estrogens, DHEA and testosterone to avoid any cancer risk or side effects. The Grow Young and Slim low-fat diet and exercise plan will also decrease and prevent fibroid tumors, uterine cysts, endometrial thickening and "heavy" periods. Typically the amount of progesterone cream can be reduced and periods are lighter, with little or no bleeding after menopause. Natural Progesterone will play a big role in restoring the imbalance caused by unopposed estrogen according to Dr. John Lee. 

 

      There are creams and herbs that support estrogen requirements, which you can obtain directly from distributors. The best creams have herbs that include: genistein and Daidzein a soy plant estrogen in capsules, other herbs that help balance the female hormone are Quercetin, Turmeric, Black Cohosh, Cayenne, Dong Quai, Hawaiian noni, Una De Gato, Ipriflavone and licorice.

 

Herbs, spices and foods (over 150 herbs) for menopause were tested for effectiveness and reported results Pro Soc Exp Biol Med 217, 1998. Soy, licorice, red clover, thyme, turmeric, hops, and verbena helped modify estrogen activity the most.  Oregano, verbena, turmeric, thyme, red clover and damiana balanced progesterone activity.

 

Black cohosh provided more relief from anxiety, depression, vaginal atrophy, hot flashes, headaches, dizziness, ringing in the ears, perspiration, palpitations, and sleep disturbances as compared to prescription drugs like valium and conjugated synthetic estrogen. Planta Medica 57, 1991, Med Welt 36, 1985, Theripeuticon 1:23, 1987, and Gyne 1:14, 1982.

 

Chaste berry after 3 months daily capsule (20 mg) reduced prolactin release and estrogen production increased. This is of benefit to menopausal women. (Arzneimittelforschung 43, 1993).

    

Kava worked better than tranquilizers in one week to reduce depression and improve feelings of well-being.  It produces a feeling of happiness, more fluent lively speech, and sound sensitivity (Pharmacopsychiatry 30, 1997).

 

St John’s Wort was found to be effective compared to placebo or antidepressants within 2 to 4 weeks to elevate mood, and reduce anxiety, depression.

 

Gingko Biloba – helps poor circulation to the brain, hands, legs, and feet (Lancet 340, 1992).  It improves memory and slows dementia within 12 weeks or less (JAMA 278, 1997).

 

     We have several women come to one of our referral medical clinics that have stopped taking those synthetic hormone pills and switched to natural hormones and herbs while enjoying the benefits of the Grow Young Diet and Exercise Plan.  These women report less fatigue, increased energy and control of mood swings.  Many women have been able to avoid hysterectomy surgery as the pain caused by fibroid tumors and uterine cysts disappeared.  Natural hormones may also reduce the incidence of Alzheimer's disease, heart disease, and colon cancer. 

 

     Estrogen is considered a new weapon against Alzheimer’s, according the journal Science, May 2, 1997, Vol. 276.  Doctor Howard Fillit treated an 80-year-old woman named Elsa with estrogen.  Prior to treatment, Elsa was quiet, apathetic, and unable to learn pairs of words, even after seeing them dozens of times.  Afterward, she was much more alert, talkative, and able to remember the words after just a few times.  The treatment with estrogen was so successful Elsa won back her mind and a marriage proposal from her boyfriend.  True love was rekindled between her and her boyfriend, a poet.  Besides Elsa, two of the six other women in the study also showed gains in their cognitive skills.  Sanjay Asthana, and his colleagues in Tacoma, Washington, reported five of six women who had mild Alzheimer’s disease and wore an estrogen patch (It would be better to use the safer, natural triple estrogen) for two months and showed improvements in verbal memory and attention.  “We found a direct relationship between the level of estrogen in the blood and improvement in memory.” The effect disappeared when the treated women went off estrogen.  The estrogen hormone may cooperate with neurotrophins, potent stimulators of nerve-cell growth in the brain, such as nerve growth factor (NGF).

    

     More and more doctors are starting to ignore advertisements to use synthetic hormones by pharmaceutical companies and they are allowing their patients the safer alternative of hormones derived from plants, wild yams or soy products.

 

     Duane Townsend, MD, director of gynecologic endoscopy and oncology at LDS Hospital in Salt Lake City recommends soy foods such as Tofu, Soy Milk, Soy Flour, Soy Ice Cream, Soy Cheese, and Soy Nuts for the genistein and Daidzein present in these foods.  The soy plant contains these isoflavones providing all the benefits women seek when taking estrogen without the side effects.  Asian women get nearly 30 to 50 mg of isoflavones daily in soy foods such as tofu, miso and tempeh, however American women only consume 1 or 2 mg of isoflavones from eating an occasional product containing soy additive! 

 

     In addition to consuming more soy based foods, Dr. Townsend has his patients take isoflavone supplements of genistein at 35 mg and increasing to 75 mg daily taken just prior to bed and first thing in the morning.  Take Daidzein at 3 to 5 mg daily with the genistein.  They are best absorbed when taken at least one or two hours after or before a meal.  Dr. Townsend says “I have found that genistein and Daidzein can work just as well as the Premarins and Estraces in terms of relieving the symptoms of PMS.  I also use it in place of HRT (synthetic estrogens) whenever a patient is willing.  Evidence shows soy supplements are more readily assimilated than synthetic estrogens or progesterones.

 

     In an Italian study, researchers gave 104 women 75 mg of isoflavones from isolated soy protein daily.  The women had a 45% reduction in hot flashes.  Bowman Gray School of Medicine in North Carolina gave 51 post menopausal women soy supplements with a marked decrease in menopausal symptoms such as mood swings, insomnia, hot flashes, vaginal irritation dry skin and improvements in blood pressure and blood lipids.       

 

     Women who switch from Synthetic hormones to soy based phyto-estrogens experience less mood changes of depression and irritability just before the menstrual cycles (Premenstrual syndrome) and after menopause.  In addition to the soy estrogen supplements and food, have your doctor switch you over to natural triple estrogen or bi estrogen, pregnenolone and progesterone.  This will closely match your body’s normal needs.

 

     Menopausal women have found natural progesterone cream, pregnenolone, DHEA, and plant based soy products, estrogen and testosterone creams (from a compound pharmacist), and oral growth factor complex keep the skin "beautiful and young" with less wrinkles.  The following steps are essential and effective for best results: Use vegetable soy based natural lotions on your skin to prevent dryness.  Your skin will radiate with health as you follow the Grow Young low-fat diet.  As your blood carries more oxygen, your skin will take on a youthful appearance in addition to adding natural hormones.

 

     To improve skin stop smoking, use cleansers on the face and skin free of toxins and chemicals (see our web site www.aginghealthy.net for recommended products), exercise and follow a water rich hydrating diet filled with vegetables, fruit.

 

     To adjust for the decrease of hormone production after menopause, which can lead to vaginal dryness, use vegetable or fruit oils such as coconut, apricot kernel, safflower, baby oil or Vitamin E oil can solve the thinning of vaginal wall tissue.  DON'T EAT THE OIL -Have your spouse apply it to the length of your vagina.  K-Y Jelly can be used, but it may dry too quickly.  Avoid oils containing alcohol, Vaseline or petroleum jelly since they can cause infection or irritation.

 

     Urinary incontinence can occur from a weak PC (pubococcygeus) muscle.  The "love muscle" is exercised by sexual intercourse or by squeezing the vagina as though trying to stop the flow of urine.  It requires daily use - at least 200 contractions per day.  Do 20 squeezes 10 times a day (at home, office, watching TV, etc.)  Squeeze and relax the muscle as rapidly as you can and end with a long, sustained contraction.  According to Dr. Kegel, these exercises have replaced the need for surgery in most women.  It also helps to increase the intensity of orgasm.  Men can also exercise their PC muscle and improve the pleasure and sensitivity of their orgasm.

 

DHEA pronounced (De‑hydro‑epi‑an‑DROS‑ter‑own) is a critical hormone, which controls several other important hormones, including serotonin, testosterone, progesterone, and estrogen.  DHEA is a hormone that can be transformed into almost any other hormone, as the body needs it. DHEA is concentrated in the brain six times more than in any other tissue or organ.  Humans produce the largest amount of DHEA as compared to other primates or other animals.  Every tissue of the human body has enzymes necessary for the metabolism of DHEA. DHEA is produced in the adrenals, ovaries, testicles and brain.

     Dr. Cranton MD has been carefully monitoring patients on small amounts of DHEA for over five years. He gave the example of a forty one-year-old man who had low levels for his age. After a few months on DHEA, his blood levels of DHEA were restored to youthful levels. He noticed his energy level was markedly higher. His skin was thicker and moister, and he was sleeping six and half-hours a night instead of eight and waking rested. He felt six or seven years younger, his sex drive increased significantly, and he said, "When you're on DHEA, it feels as if every cell in your body is just humming."

 

     A female patient with Asthma experienced astonishing results, she said, "Within an hour after taking my first capsule of DHEA, I suddenly found I could breathe again. That month my period, which had been irregular, went back to normal…‑I was on my old regular twenty‑seven day cycle‑and my headaches disappeared. My depression lifted within the first few days.  Two months after I started DHEA I joined a dance class.  It had always been a childhood dream to dance.  I feel like a teenager, as if I were renewing myself."  Large amounts of additional water intake can help transport hormones like DHEA more effectively and can help further reduce symptoms of Asthma, headaches and depression.

 

     This tremendous amount of DHEA present during youth has intrigued longevity researchers. DHEA drops to near zero in all people at death. Will we prolong life an additional ten or twenty years if we take supplements of DHEA to maintain youthful levels?  Studies show that an increase in blood levels of DHEA sulfate is associated with a 36% less mortality rate from any cause.

 

     Dr. Yen reported in the Journal of Clinical Endocrinology and Metabolism 1994 giving men and women age 40 to 70 years old, DHEA (50 mg taken orally) at bedtime for 6 months. In two weeks the blood levels of DHEA were restored to youthful levels (double blind, placebo crossover study). There was a remarkable increase in perceived physical and psychological well being in 67% of the men and 84% of the women. The participants said they slept better, had more energy, and handled stress better, with no side effects.  DHEA helps maintain the immune system, providing a protein sparing effect while improving levels.  They discovered that supplementing DHEA after only six months helped prevent aging with a 10% increase in Insulin like Growth Factor (IGF‑1) levels and a 19% decline in Binding Protein (IGFBP‑1) creating a 50% ratio improvement.

 

     Benefits of DHEA, according to over 2,500 published papers, are DHEA decreases abnormal platelet aggregation and LDL (“bad”) cholesterol levels. This reduces the risk of heart attacks and stroke. DHEA enhances the immune system and the thymus gland, reduces the rate of infection, Epstein Bar, Lupus, herpes and cancer.  DHEA reduces the stress hormone cortisol and helps offset caffeine and the catabolic effects of exercise.  DHEA increases serotonin naturally, which decreases food consumption and helps speed weight loss, according to The Journal of Clinical Endocrinology and Metabolism 1995.

 

     DHEA declines from heavy alcohol drinking, birth control pills, stress, hypothyroidism, and lack of exercise and obesity. More is not necessarily better in the case of hormone replacement. High dosages of DHEA (1,600 mg a day) can cause acne, unwanted hair growth, irritability, headaches, and rapid heart beat. If you are having any side effects, reduce the dosage gradually down to lower intakes. Have your DHEA levels checked by saliva tests to monitor your progress and maintain ideal levels.

 

     DHEA is available as liquid sublingual under the tongue or transdermal cream applied to the skin, or capsules and tablets.  Precursors of DHEA from wild yam do not convert very well into DHEA, so I prefer to use the actual DHEA pharmaceutical grade.  I don’t believe you should take high dosages of this powerful hormone, because in proper amounts you can gradually restore your levels to an ideal range.  Capsules and tablets are to be taken in amounts less than 25 mg per day so it doesn’t convert into undesirable by products of estrogen.  When you use creams or spray the dosage is much less.  DHEA spray requires only 1.2 to 2 mg a day.  You only need between 2 to 15 mg in cream because our skin allows for direct absorption to our tissues and cells.  Stay with these low dosages and allow your body time to adjust and build up gradually to avoid possible side effects of excess use of DHEA.  We advice against high dosages beyond 50 mg to avoid any overproduction of estrogen which could lead to future problems. Be sure that if you’re a man taking DHEA in capsule form above 50 mg, you have your estrogen levels monitored on a regular basis.  Men given 100 mg of DHEA in capsule form experienced an undesirable increase in Estrogen. (E1-Estrone increased over 226% above baseline from 100 pmol/L to over 300 pmol/L and E2-Estradiol increased 137% from 40 pmol/L to 60 or 70 pmol/L).  Men had almost no change in Free and total testosterone. Both men and women showed an increase in androstenedione.

    

     Surprisingly, there was no increase of estrogen in the women using DHEA at 50 or 100 mg, however women did have an increase in testosterone androgens. The researchers cautioned to not use more than 50 mg in capsule form, however, DHEA in cream form at 20% used in a daily dose of 10 ml was the best, because it safely increased DHEA without affecting estrogen in men or testosterone in women- JCEM 1999:84, 6, 2170-6.  DHEA taken in lower, proper dosages as listed on the label in tablet form, in cream form or sublingual helps to burn excess calories instead of storing glycogen.  Obese people tend to have higher insulin levels.  DHEA helps to lower insulin levels by pushing glucose into your cells to be burned.  DHEA helps reduce appetite by creating a feeling of "fullness". 

 

     Dr. Bill Timmins suggests you also monitor cortisol levels morning 6am to 7am, noon, afternoon 2pm to 3pm and evening 10 p.m. to midnight.  Too high of cortisol levels shows you are under excess stress and can cause catabolism or break down of tissue and premature aging.  If you have stressfully high cortisol levels you need to get to sleep by 10 pm, take a meditation break or nap, eat more frequent small meals and use DHEA to balance cortisol.

 

     Too low of cortisol levels alert you that you are at risk for adrenal failure, fatigue and aging faster than normal.  Using licorice extract sublingual, 10 drops under the tongue at the times of the day or evening where you measure low can restore low cortisol levels.  Licorice extract will increase the ACTH levels that will bring cortisol back up to a normal range.  While the proper amount of sleep helps reduce stress and reduce elevated cortisol levels, adequate sleep helps bring depressed cortisol levels back into a healthier range.  Here again, it is best to get to bed no later than 10 p.m. every night and allow your body recovery time during sleep to heal and rest.  Most of the important hormones are restored during the hours of 10 p.m. and 2am.  You might consider getting to bed earlier, and if you wake refreshed earlier in the morning you can get up and do some productive things, then take a nap in the morning before your long day.  Also eat frequent small meals with sufficient calories to stay at your ideal body weight and to maintain proper blood sugar and insulin control.  Exercise helps reduce stress and excessive exercise can create more stress.  Exercise consistent and sensibly.  Proper sleep, nutrition and exercise can help prevent adrenal stress, burnout or failure. 

 

     I monitor all my hormones on a regular basis, both by saliva and blood to keep in optimum range, and adjust my dosages of each hormone.  I was surprised to find how low my cortisol level and melatonin was, and that after using supplements my testosterone was much higher than it needed to be.  Even though my DHEA level was low, I learned from Dr. Timmins work that I needed to bring my cortisol up by using licorice root.  This would bring my DHEA level back up to a better range.  It was not enough to just take DHEA.  I also found out what effect DHEA had on my testosterone and my estradiol levels when I tested DHEA in spray form, cream form compared to tablet.  My free testosterone measured by saliva increased too high from 49 pg. to 100 pg. after taking 2 mg DHEA three times a day for only six days.  So I learned I could reduce my dosage of DHEA down to one time a day in spray form and reduce or stop my use of testosterone cream and switch to only the herbs.  The doctor working with the lab called me about the results because he was surprised by how high my testosterone was.  This is a good reason to have your levels checked and monitored to maintain ideal levels, not excessive or allowing deficient hormone levels. 

 

     DHEA has many of the benefits of estrogen, with little or no side effects. It helps women with vaginal atrophy to stimulate the cellular growth of the vaginal wall, increased vaginal secretion, thus restoring the vagina to its youthful condition. Studies on female cancer patients that had ovaries removed reported little or no change in sex drive. The ovaries produce estrogen and testosterone. However, after removal of the Adrenal glands, the site of DHEA production, four out of five women experienced a total loss of sexual desire and responsiveness. A combination of DHEA, Free Testosterone and growth hormone are the most important hormones for sexual interest and desire in women.

 

     DHEA produces the pheromones that emit our scent through the skin. Pheromones act on our brain to receive the scent of the opposite sex.  It may influence our choice of mate, if we become pregnant, and the bonding with our babies. The fetus produces two hundred to eight hundred times higher amounts of DHEA than the levels of progesterone, testosterone, and estrogen.

 

Thyroid

Thyroid is another anti aging hormone to monitor.  If your thyroid level is low try taking supplements of glandulars, desiccated thyroid, (1/4 – grain per serving) or Armour. This is a natural form providing T3 and T4 that is more like that which the thyroid gland produces. People will feel better on it. Dr. Neil Rouzier encourages his patients to use compound Armour morning and night.  Armour from a compound pharmacist can be more effective at 1 to 2 grams.  Regular Armour may  require a higher dosage to correct people with very low thyroid levels.  Also be sure to use kelp for the iodine necessary for thyroid metabolism.

 

     For years doctors have known that if a person has a low thyroid that he should have that thyroid level replaced.  I don’t think that there is a doctor in the country that would argue this and yet for various reasons some doctors are reluctant to understand the great advantage to replacing natural human growth hormone, DHEA, melatonin, and other associated hormones that are so critical.  We have learned that progesterone improves thyroid activity.

 

     When my partner Shawna started taking a natural thyroid replacement (thyroplex suggested by Jonathan Wright MD from Kent Washington, and herbs-Black Walnut, Norwegian Kelp). I remember very distinctly that in a matter of a few days some of the changes that I noted were a change in her body temperature.  Her hands always seemed to be cold even in rather warm weather and she became a rather hot bodied person.  She formerly was very embarrassed to shake anyone’s hand because her hands were always so cold.  On particularly cold days she would become almost immobilized. The natural thyroid replacement worked very well for her.  She has also noted that if she runs out of her supply her levels start to decline again.  Our web site www.aginghealthy.net lists the best thyroid stimulating herbs that you can purchase direct.

 

Thyroid & Thyroid Stimulating Hormone TSH benefits include:

q       Improved sex drive, energy, less fatigue, and stronger

q       Less colds, viruses, respiratory ailments, better breathing

q       Warm hands & feet, stronger heart pump action

q       Less muscle cramps, reduced low back pain, stiff joints, arthritis

q       Prevent bruising, less dry skin & leathery skin; avoid brittle nails, hair loss.

q       Ideal thyroid levels help mental acuity, improve memory, less emotional crying, upset

q       Reduce Atherosclerosis, less headaches

 

Melatonin

     A startling experiment on anti‑aging demonstrated the power of melatonin, the actual hormone that controls the aging clock. The scientists transplanted the pineal gland from old mice into the young mice. They took the pineal gland from the young mice and transplanted it into the old mice. Melatonin is released in smaller quantities from the pineal gland as we age. The transformation was incredible! The older mice looked younger, with rejuvenated bodies. They were more active with a 30% extension in life span. The young mice with the old pineal gland aged rapidly and died 30% sooner than normal. The aging clock had finally unlocked the mysterious mechanism that determines not only how we age but also why we age based on a study of multiple hormones.

 

     The pineal gland in humans also sends out a message through melatonin to preserve the organs and the body in a healthy state however, the majority of melatonin is produced in the human gut. Some people produce unusually large amounts of melatonin during sleep and others produce small amount of melatonin during sleep.  The most amount of melatonin is produced during sleeping hours of 10 p.m. until 2 a.m.  After 2 a.m. our melatonin levels decline rather rapidly reaching the lowest levels during daylight.  We can test saliva levels of melatonin by setting an alarm  to 2am alarm and upon waking, spit into a vial at bed side. Another tube is collected just prior to sleep and the last tube upon waking the morning to get the range of melatonin (see ideal reference range at end of chapter).  Unfortunately, we have created artificial day light with the use of lamps, light fixtures, car headlights, and streetlights. It is a necessity for the current societies fast pace lifestyle however, the presences of this artificial lighting drastically decreases our natural ability to produce melatonin.  In primitive times our ancestors went to sleep at dusk and woke at dawn. Early to sleep and early to rise might be an important factor in preserving youth.  The Pineal gland is connected directly to the nerve sensors in our eyes.  If light is present at night our brains are tricked into thinking we don’t need to sleep or to produce melatonin, the magical substance that allows us to go into a deep restful sleep.  Darken your room at night, and wear blinders over your eyes if your spouse reads with a lamp.  Also, if you have a radio playing all night the radio waves will interfer with melatonin production and decrease the quality of sleep.

 

     Because of artificial light and because of the aging process, we must replace the dwindling melatonin to continue to preserve youth.  It's best to take very small amounts of melatonin of one-tenth to one half mg (up to five mg) a night sublingual, dissolved under the tongue before you go to sleep. Increase gradually, so that you awaken in the morning alert and rested. If you awaken groggy, reduce the dosage back down by one half-milligram increment. Melatonin acts like a natural sleeping pill, enhancing REM dream sleep. Melatonin reduces jet lag, and resets the biological clock. In a marriage, day people and night people can learn to match their schedule using melatonin. The person that tends to stay up late can take Melatonin at the time their spouse wants to go to sleep.

 

     Melatonin has other benefits, according to the New England Journal of Medicine, January 16,1997. It is one of the most powerful free radical scavengers serving as an antioxidant inside the cells. For this reason melatonin can instantly de-activate dangerous hydroxyl molecules that are present with every breath we take.  Researchers believe this may be one of the keys to preventing cancer and slowing the aging process.  Melatonin also lowers cholesterol, heart disease, and cataracts. It may help Parkinson's disease, Alzheimer's and asthma and keep you young, vigorous and sexually rejuvenated.

 

     Some people get worried that if they take hormone replacements that it will shut down their own body systems production. However, by augmenting and replacing that level that has declined due to aging, we are restoring it to a more youthful level. At youthful levels, we gain the benefit from natural and ideal levels of hormone replacement.  If people stop taking the therapy after three months, they don’t immediately revert back to a lower level compared to levels prior to therapy.  The benefits they gained from the biochemical hormones remain for several weeks or months. However, without the supplements you will begin to notice the differences.  Our brain and neural systems contain enzymes and steroid precursors such as cholesterol to convert into a variety of over 150 steroid and neurosteroid hormones. Scientists are still discovering new biochemical hormones that are created from the eight critical hormones.

 

     William Regelson MD, age 71, has been taking DHEA everyday and one‑tenth of a milligram of melatonin every night for eleven years. "I feel the difference.  We need to treat aging as a disease, not just an irreversible condition." Dr. Regelson is a researcher at the Medical College of Virginia in Richmond.

 

     Dr. Cranton MD told the story of a man age 72 years old who felt as if his life was winding down. He had no energy, reduced muscle tone, and he was falling asleep while driving. After eight months of hormone replacement he no longer needs as much sleep and he does not fall asleep while driving. The muscles in his legs and arms are strong and hardening. Now he runs up the steps in his house "as if I were twenty years younger.  I thought my life was almost over, but now I’m planning to go to one hundred.”

 

     Now that you have learned about the latest research on anti‑aging and hormone replacement let's not forget the important principals of healthy eating. People who want to look and feel great will do the following. I encourage the use of whole food concentrates, antioxidant's vitamin A, E, C, B complex and whole food origins for minerals. Eat as much raw food as possible in the form of vegetables, fruit, sprouted seeds, sprouted beans and sprouted grains. I use a Vita‑mix whole food machine or a simple blender to blend whole vegetables and fruit, retaining the fiber and all the vitamins, minerals and organic pure water. Use gluten and soy replacements for meat and rice milk for dairy product substitutes. Frequently nibble small meals, whenever you feel empty or hungry.

 

     Exercise and activity has also been proven to reverse and slow aging. By following the Grow Young hormone replacement program you will have more energy to be able to workout with weights and do aerobics at least three times a week. Be physical and active. Enjoy holding, hugs, kisses and intimacy. Physical activity and intimacy will also increase your natural hormone production.

 

     What can you expect from the Grow Young Again program? After only nine days most people will notice an improvement in energy levels, mental abilities, sleep habits, and sexual energy.  After 90 days the fat on your body will begin to melt away using only natural approaches to enhance your body's proper metabolic levels. Your new Fountain of Youth habits will allow you to look and feel years younger.  Your family and friends will notice the transformation and ask you what you have done.  Dr. Eugene Shippen believes we should test younger people at age 25 or 30 to get a baseline for future reference to compare declining levels.  As people then age replacement of natural hormones can then be done to increase levels to what was correct forthat person.  Unfortunately, most doctors are not doing these baseline tests, so this section can give you some guidelines.  However, many anti-aging doctors still suggest the improvement or reduction in symptoms is far more important than the final levels or lab values.

 

Grow Young Hormone Testing

Male Panel

Our suggested male panel was designed to be very complete including tests for Chemistry and lipid panel, CBC, Estradiol, Estrone, Free Testosterone, total testosterone, Dihydrotestosterone, PSA-Prostate specific antigen, Somatomedin C (IGF-1), DHEA-S, Pregnenolone, progesterone, Thyroid Free T3, TSH, Free T4.

 

Female Panel

Our suggested female panel includes, Estradiol Progesterone, total testosterone and free, DHEA-S, Somatomedin C (IGF-1), Pregnenolone, Chemistry and lipid panel, CBC, Free T3, TSH, Free T4. Other key hormones not tested here are melatonin and cortisol since their variations are better measured by saliva.

 

Additional tests depending on your budget (check doctor and lab fees)

1. Sex Hormone Binding Globlin (SHBG).  2. The above panel includes one type of Estrogen (Estradiol) however you can test for all three estrogens E1- Estrone, E2-Estradiol, E3-Estriol. 

3. Insulin fasting in am and postparandiol after eating 4. Growth Hormone after 5 days spray.

 

URINE testing for hormones detects variations of 8 hormones, however, saliva tests will pick up the day and night variations, is simplier to test, and doesn’t alter your hormones by the fear of a needle. Saliva is becoming more accepted as an excellent way to monitor your hormone levels.  Ask an anti aging doctor about your personal test needs.

 

Ideal vs. deficient blood / saliva hormone levels

 All tests performed Fasting in the morning, water only.

1. Somatomedin C (IGF-1) Ideal levels 250 to 450 ng/ml

Somatomedin C is the test to measure growth hormone. Be sure to consistently use oral Growth hormone complex and factors several times a day and evening to preserve health and quality of life.  Youngsters less than 5 years are under 220 ng, age 8 to 9 go to 300 to 400.  During the most rapid growth period, age 12 to 15, have levels near 1,000 ng/ml, as adults our levels rarely exceed 450 ng/ml.

 

2. Human Growth Hormone after 5 days oral use of product*

Supplement levels under .5 ng/ml

**After challenge product use 2 ng/ml to 12 ng/ml

**A challenge test normal design is after ingestion of product or food being tested.

 

3. Pregnenolone ideal levels 50 to 200 ng/dl

Adult male and female levels

Standard 20-150 ng/dl

 

4. Free Testosterone

Ideal levels 100 to 500 ng/dl  or  19 to 40 pg/ml

Standard levels:

Men average range 84 to 402 ng/dl  or  8 to 55 pg/ml

Deficient for Men is 1 to 9 pg/ml, need supplement herbs 

Women standard range  .9 to 3.9 ng/ml

Deficient for Women is .3 to 2.7 pg/ml need supplement herbs

 

5. Total Testosterone

Ideal levels 500 to 1200 ng/dl for Men, Ideal levels  80 to 120 ng/dl for Women

Men age    Range ng/dl        Women ng/dl

20-49                             286-1511            63-120  Ovulating

>50                  212-742              49-113   Postmenopausal

Supplement levels (Avena Sativa herbs used morning and evening)

if under 400 ng/dl in Men.  If under 250 ng/dl have your doctor prescribe natural testosterone cream used one or two hours before bedtime.  Women levels under 30 ng/dl need herbs.

 

      Ideal blood levels for total testosterone for men is 500 to 1200 Ng/dl (nanograms per deciliter). Men with low levels of less than 400 Ng/dl bearing watching and under 250 Ng/dl need treatment.  If you restore these low testosterone levels to what they should be you may feel like you were 25 years old again!  By the age of 30 free testosterone levels start to drop gradually with age. Free testosterone blood levels for men should be 19 to 40 pg./ml. Men with low free testosterone levels of 1 to 9 pg./ml could benefit from supplement therapy. The ratio of testosterone to estrogen has been found to be very important. The Estrone levels for men should be between 10 to 30 pg/ml ideally and never above 65 pg/ml.

 

     Salivary testosterone levels normal for men are 200 to 400 pmol/L or 30 to 120 pg/ml.  Men with saliva levels less than 120 pmol/L or under 30 pg/ml can benefit from testosterone enhancing supplements.

    

     Expected range for women salivary testosterone is 80 to 155 pmol/L.  Levels less than 80 will certainly need herbs and supplements to release testosterone.  Blood tests for free testosterone .9 to 3.9 ng/ml during ovulation, age 20 to 29 is normal, and normal for female total testosterone levels is 30 to 100 Ng/dl. This is the time when women are most fertile.  Past the age of 50, postmenopausal women have their lowest blood levels of free testosterone at .3 to 2.7 pg./ml.  Past the age of 40, menopausal women's total testosterone levels can drop to zero to 64 Ng/dI.  If a women’s level drops lower than 30 Ng/dl she will not have an satisfactory sex drive, reduced energy, lose of muscle tone and she will benefit from herbs and testosterone replacement to restore a range of 30 to 60 Ng/dl.

 

     For women it is best to stay in the youthful range between .9 and 3.9 ng/ml blood free testosterone and 30 to 100 Ng/dl total testosterone, and 80 to 155 pmol/L saliva or 5 to 18 pg/ml; not too low or too high. Excessive levels of testosterone in women can occur from ovarian or adrenal disorders or excessive dosages of supplements leading to acne, increased body hair growth, deepening of the voice or balding.  By proper monitoring of tests and symptoms women don’t have to worry about getting too much.  The real problem is not enough testosterone as she ages.

 

6. Sex Hormone Binding Globlin (SHBG)

This binding protein increases as we age, binding testosterone and estrogen causing premature aging.  Certain herbs and vegetables prevent binding.  Dr. Eugene Shippen has found that a male could have a high testosterone of 600 yet if the SHBG is too high your body won’t have enough free testosterone.  Herbs, HCG and testosteron can help reduce SHBG and restore free testosterone levels.

Male  age

age  20 to 40        13 to 71 nmol/L

age  40 to 79       18 to 125 nmol/L

Female age

Age 50 to 79         8 to 114 nmol/L

 

7. Dihydrotestosterone (DHT)

Standard ranges

Male age

25 to 90    40  to 1,000 pg/ml

Female age

25 to 90      5 tp 178 pg/ml

High levels in females can be a sign of using too much DHEA converting to androstenedione and then to DHT. 

Excessive levels in males (over 1,000) usually come from using too much testosterone.  Reduce the dosage and frequency, and depend more on herbs.

DHT at high levels may cause acne or hair loss in some people.  DHT is a libido enhancer.  Dr. Neal Rouzier has suggested it is best not to use proscar to reduce DHT because you will lose libido.                           

 

8. PSA-Prostate specific antigen Male test for healthy prostate free of tumors less than 4 ng/ml, the higher levels more risk.  We are finding estrogen levels in men low may be more important than restricting testosterone to prevent prostate problems.  Hormone replacement of testosterone initially may increase PSA yet it will reduce or level off over time.  Dr. Shippen has found men montored by a digital rectal exam and biopsy (in men with cancer), that most men will do fine with testosterone cream provided they are monitored.

 

9. DHEA-S

Ideal serum levels for men 450 to 600 mg/dl and women 300 to 400 mg/dl. Ideal levels for DHEA (free unbound) is 700 to 1200 ng/dl for men and 450 to 800 ng/dl women.  DHEA is highest in the morning lowest in the evening.

Standard serum levels

Men age    Range (ug/dl)    Women age  Range (ug/dl)

15-39          150-550            15-29           100-500 

40-49          100-400            30-39             60-350

50-59            60-300            40-49             40-250

>60               30-200            >50                20-150

Deficient levels under 250, Male or Female need Supplement DHEA, cream or low dosage liquid or capsules.  The goal is to bring DHEA sulfate and Free DHEA combined, to youthful levels of a person aged 20 to 25.

Saliva ideal levels for DHEA in men 10.9 to 16/9 Nmol/L or 200 to 300 pg/ml.  Ideal for women 7.2 to 8.5 Nmol/L or 125 to 170 pg/ml

 

10. Thyroid Panel

Free T3 range 2.3 to 4.2 pg/ml  or 25 to 37 UT

T3 gives or tells all the cells of the body how fast to function.  The gives off body heat, and when the body’s enzymes get cold (low temperature) that’s when all the individual’s symptoms appear.  Stress (physical, emotional, mental) the body slows down the metabolism by decreasing the amount of raw material T4 that is converted to the active thyroid hormone T3. This is done to conserve energy and is normal, but when the stress is over, the metabolism is supposed to speed back up to normal.  An enzyme called Reverse T3 starts to build up in some people and levels start to drop more and the person feels worse.  By taking natural T3 glandular thryoid (Armour compound is best) the levels can be restored.  TSH Female and Male range .35 to 5.50 uiu/ml.  Free T4 Range 4.5 to 12 RIA

11. Progesterone Ideal over 4 ng/ml, females range from 4 to 25 (higher if pregnant 90 to 400 ng/ml).  Male range 1 to 10.  Dr. Shippen said men may use small amounts of progesterone cream to help prostate sexual function.  Too much prgesterone or estrogen in men could cause breast enlargement and weight gain.

 

12. Estrogens: the 3 types are Estradiol, Estrone, Estriol

As a general guide for women, first use phytoestrogens from plant derived sources, however after you reduce to your ideal weight and you have continued symptoms of “estrogen dominance”, then you will need a natural tri-estrogen cream replacement.  This can be provided in the lowest dosage prescribed by your doctor.  An Estrogen cream containing 80% estriol (1 to 4 mg ) and a smaller amount of estradiol (.25 to .5 mg) and estrone (.3 to .625 mg) will alleviate such PMS symptom, swollen, tender breasts, weight gain, mood swings, and cramps or vaginal dryness.  Use the lowest dosage that works, or take the cream every other day or every third day.  If you just have vaginal dryness or atrophy, then apply an estriol cream vaginally a few times a week.  The use of any estrogen must be combined in use with natural progesterone cream, with or without a uterus or ovaries.  Men need to maintain low estrogen levels, although some is needed for the brain and healthy skin, excessive levels over 50 pg/ml of Estradiol or Estrone can cause loss of sex function, crying, fat gain and prostate enlargement.  Certain herbs, the low-fat water rich food plan with exercise is a major part of control.  Beware of over use of DHEA or testosterone that can convert into too much estrogen.

     Estradiol-E2 Ideal female levels is a wide range depending on phase of life and time of menstrual cycle lasting 28 to 40 days.  The Estradiol is the most powerful estrogen.  The saliva ranges from .5 to 5 pg/ml during the menstrual phase (estrogen low) which includes day one to 7 of bleeding and the Follicular phase (estrogen rise) lasts from day 6 to 14 days (until a surge of LH and the release of the egg).  The ideal Estradiol peak is 4 to 14 pg/ml during ovulation phase or mid-cycle (the release of the egg) lasting 2 to 3 days.  The